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Rx 阿司匹林肠溶片(石药)(医)

会员价:会员可见 此品种为效期品种

生产厂家:#石药集团欧意药业有限公司

包装规格:100mg*36片 2

包装单位:个

件装量:600

中包装:1

效期2021-06-08

批准文号:国药准字H20153035

数量- + 库存:充裕
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  • 生产厂家:#石药集团欧意药业有限公司

    包装单位:个

    药品规格:100mg*36片 2

    批准文号:国药准字H20153035

    件 装 量:600

    • 【产品名称】阿司匹林肠溶片
    • 【规格】100mg*30片
    • 【主要成份】阿司匹林。
    • 【性状】本品为白色肠溶包衣片,除去包衣后显白色。
    • 【功能主治/适应症】

      阿司匹林对血小板聚集的抑制作用,因此本品适应症如下:降低急性心肌梗死疑似患者的发病风险。预防心肌梗死复发。中风的二级预防。降低短暂性脑缺血发作(TIA)及其继发脑卒中的风险。降低稳定性和不稳定性心绞痛患者的发病风险。动脉外科手术或介入手术后,如经皮冠脉腔内成形术(PTCA),冠状动脉旁路术(CABG),颈动脉内膜剥离术,动静脉分流术。预防大手术后深静脉血栓和肺栓塞。降低心血管危险因素者(冠心病家族史、糖尿病、血脂异常、高血压、肥胖、抽烟史、年龄大于50岁者)心肌梗死发作的风险。

    • 【用法用量】用法:口服。肠溶片应饭前用适量水送服。降低急性心肌梗死疑似患者的发病风险:建议首次剂量300mg,嚼碎后服用以快速吸收。以后每天100-200mg。预防心肌梗死复发:每天100-300mg。中风的二级预防:每天100-300mg。降低短暂性脑缺血发作(TIA)及其继发脑卒中的风险:每天100-300mg。降低稳定性和不稳定性心绞痛患者的发病风险:每天100-300mg。动脉外科手术或介入手术后,如经皮冠脉腔内成形术(PTCA),冠状动脉旁路术(CABG),颈动脉内膜剥离术,动静脉分流术:每天100-300mg。预防大手术后深静脉血栓和肺栓塞:每天100-200mg。降低心血管危险因素者(冠心病家族史、糖尿病、血脂异常、高血压、肥胖、抽烟史、年龄大于50岁者)心肌梗死发作的风险:每天100mg。
    • 【不良反应】所列出的药物不良反应(ADRs)是基于所有阿司匹林制剂(包括短期和长期口服治疗)的上市后自发报告,因此无需按照CIOMSⅢ频率类别进行组织。上、下胃肠道不适,如消化不良、胃肠道和腹部疼痛。罕见的胃肠道炎症、胃十二指肠溃疡。非常罕见的可能出现胃肠道出血和穿孔,伴有实验室异常和临床症状。由于阿司匹林对血小板的抑制作用,阿司匹林可能增加出血的风险。已观察到的出血包括手术期间出血,血肿,鼻衄,泌尿生殖器出血,牙龈出血。也有罕见至极罕见出血的报道,如胃肠道出血、脑出血(血压控制不良的高血压患者和,或与抗凝血药台用),可能威胁生命。急性或慢性出血后可能导致贫血,缺铁性贫血(如隐性的微出血),伴有实验室异常和临床症状,例如虚弱,苍白,低血压。严重葡萄糖-6-磷酸脱氨酶(G6PD)缺乏症患者出现溶血和溶血性贫血。肾损伤和急性肾衰竭。过敏反应伴有相应实验室异常和临床症状,包括哮喘症状,轻度至中度的皮肤反应。呼吸道、胃肠道和心血管系统,包括皮疹,荨麻疹,水肿,瘙痒症,心血管-呼吸系统不适,极罕见的严重反应包括过敏性休克。极罕见的一过性肝损害伴肝转氨酶升高。药物过量时曾报道头晕和耳鸣。
    • 【禁忌】下列情况禁用阿司匹林肠溶片:对阿司匹林或其它水杨酸盐,或药品的任何其它成份过敏;水杨酸盐或含水杨酸物质、非甾体抗炎药导致哮喘的历史;急性胃肠道溃疡;出血体质;严重的肾功能衰竭;严重的肝功能衰竭;严重的心功能衰竭;与氨甲蝶呤(剂量为15mg/周或更多)合用(见药物相互作用);妊娠的最后三个月。
    • 【注意事项】下列情况时使用阿司匹林肠溶片应谨慎:对止痛药/抗炎药抗风湿药过敏,或存在其它过敏反应。胃十二指肠溃疡史,包括慢性溃疡、复发性溃疡、胃肠道出血史。与抗凝药合用(见药物相互作用)。对于肾功能或心血管循环受损的患者(例如,肾血管性疾病、充血性心衰,血容量不足、大手术、败血症或严重出血性事件),乙酰水杨酸可能进一步增加肾脏受损和急性肾衰竭的风险。对于严重葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症患者,乙酰水杨酸可能诱导溶血或者溶血性贫血。可增加溶血风险的因素如高剂量、发热和急性感染。肝功能损害;布洛芬可能干扰阿司匹林肠溶片的作用。如患者合用阿司匹林和布洛芬,应咨询医生。阿司匹林可能导致支气管痉挛并引起哮喘发作或其它过敏反应。危险因素包括支气管哮喘,花粉热,鼻息肉,或慢性呼吸道感染。这也适用于对其它物质有过敏反应的患者(例如皮肤反应、瘙痒、风疹)。由于阿司匹林对血小板聚集的抑制作用可持续数天,可能导致手术中或手术后增加出血。低剂量阿司匹林减少尿酸的消除,可诱发痛风。
    • 【药物相互作用】本品可增加以下药物的作用:1.抗凝血药。2.同时使用含可的松或可的松类似物的药物、或同时饮酒时引起的胃肠道出血危险。3.某些降血糖药。4.氨甲喋呤。5.地高辛,巴比妥类,锂。6.某些震痛药、抗炎药和抗风湿药,以及一般抗风湿药;7.某些抗生素。8.三碘甲状腺氨酸。本品可减弱以下药物的作用:1.某些利尿药。2.降压药。3.促尿酸排泄的抗风湿药。拜阿司匹林和以上药物合用时应在医生的指导下进行,此情况也适用于近期曾经服用的药物。服药时不可饮酒。
    • 【孕妇及哺乳期妇女用药】1.怀孕早期及中期时慎用本品。因本品在分娩时可增加母亲和新生儿发生并发症的危险,故妊娠最后3个月的妇女禁用阿司匹林肠溶片。2.乙酸水杨和它的降解产物能少量进入母乳,哺乳期妇女应慎用。服用大剂量时(每天超过150mg)应终止哺乳。
    • 【老年患者用药】老年患者若肾功能下降服用本品易出现不良反应,因此肾功能下降的老年患者应慎用本品。
    • 【药理毒理】乙酰水杨酸使血小板的环氧合酶(即前裂腺素合成酶)乙酰化,从而减少血栓素A2(TXA2)的生成,对TXA2诱导的血小板聚集产生不可逆的抑制作用;对ADP或肾上腺素诱导的II相聚集也有阻抑作用;并可抑制低浓度胶原、疑血酶、抗原抗体复合物、某些病毒和细菌所致的血小板聚集和释放反应及自发性聚集,由此预防血栓的形成。高浓度时,乙酰水杨酸也能抑制血管壁中PG合成酶,减少前列环素(PGI2)的合成,而PGI2是TXA2的生理对抗菌素剂,它的合成减少可能促成血栓形成。
    • 【药物过量】1.轻度:即水杨酸反应,表现为头疼、头晕、耳鸣、耳聋、呕吐、腹泻、精神紊乱、多汗、呼吸急促、烦渴、手足不自主(多见于老年人)及视力障碍等。2.重度:可出现血尿、抽搐、幻觉、重症精神紊乱、呼吸困难及无名热等,儿童患者精神及呼吸障碍更明显。过量时,实验室检查可有脑电图异常、酸碱平衡紊乱(呼吸性碱中毒及代谢性酸中毒)、低血糖或高血糖、酮尿、低钠血症、低钾血症及蛋白尿。
    • 【药代动力学】阿司匹林口服后主要在小肠上部吸收,3.5小时左右血药浓度达峰值,吸收后迅速被水解为水杨酸,因此乙酰水杨酸血泺浓度低,血浆半衰期为0.38小时,平均驻留时间为3.9小时,水解后以水杨酸盐的形式迅速分布至全身组织,也可进入关节腔及脑脊液,并可通过胎盘。水杨酸与血浆蛋白结合率高,可达80-90%,水杨酸经肝脏代谢,代谢物主要为水杨尿酸及葡萄糖醛酸结合物,小部分为龙胆酸。本品大部分以结合的代谢物,小部分以游离的水杨酸从肾脏排出。尿液pH值对排泄速度有影响,在碱性尿中排泄速度加快。
    • 【贮藏】密封,在干燥处保存。
    • 【有效期】24个月。
    • 【生产厂家】石药集团欧意药业有限公司
    • 【批准文号】国药准字H20153035
    • 【生产地址】石家庄经济技术开发区海南路99号
    • 【条形码】6916119031535

0
399.98msRequest Duration4MBMemory UsageGET goodsRoute
    • Booting (255.87ms)
    • Application (167.14ms)
      12 templates were rendered
      • goods.show (resources/views_new/goods/show.blade.php)6blade
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      • layouts.nav_top (resources/views_new/layouts/nav_top.blade.php)13blade
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      uri
      GET goods
      as
      goods.index
      controller
      App\Http\Controllers\GoodsController@index
      namespace
      App\Http\Controllers
      prefix
      null
      where
      file
      app/Http/Controllers/GoodsController.php:32-37
      23 statements were executed, 6 of which were duplicated, 17 unique57.74ms
      • select * from `ecs_goods` where `ecs_goods`.`is_delete` = '0' and `online` = '1' and `off_sale_ranks` != '1,2,5,7,8,9' and `goods_id` = '929' and `is_delete` = '0' limit 12.73msys_test
        Metadata
        Bindings
        • 0. 0
        • 1. 1
        • 2. 1,2,5,7,8,9
        • 3. 929
        • 4. 0
        Hints
        • Use SELECT * only if you need all columns from table
        • The != operator is not standard. Use the <> operator to test for inequality instead.
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • select * from `ecs_goods_attr` where `ecs_goods_attr`.`goods_id` in ('929')2.51msys_test
        Metadata
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        • 0. 929
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_goods_attribute` where `ecs_goods_attribute`.`goods_id` in ('929')2.04msys_test
        Metadata
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        • 0. 929
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        • Use SELECT * only if you need all columns from table
      • select * from `ecs_member_price` where `ecs_member_price`.`goods_id` in ('929')2.4msys_test
        Metadata
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        • 0. 929
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_goods_sms` where `ecs_goods_sms`.`goods_id` in ('929')2.69msys_test
        Metadata
        Bindings
        • 0. 929
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_goods_zp_region` where `region_id` = '8'2.25msys_test
        Metadata
        Bindings
        • 0. 8
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_goods_zp` where `ecs_goods_zp`.`goods_id` in ('929') and `enabled` = '1' and `start` < '1746362814' and `end` > '1746362814' and `is_delete` = '0' and `id` in ('1', '2', '3', '4', '5', '6', '7', '8', '9', '11', '12', '13', '14', '15', '17', '18', '19', '20', '21', '22', '23', '24', '25', '26', '27', '28', '29', '30', '31', '32', '33', '34', '35', '36', '37', '38', '39', '40', '41', '42', '43', '44', '45', '46', '47', '48', '49', '50', '51', '53', '54', '55', '58', '59', '62', '60', '61', '69', '72', '73', '75', '77', '76', '79', '80', '86', '85', '87') order by `goods_number` desc2.5msys_test
        Metadata
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        • 3. 1746362814
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        • 65. 75
        • 66. 77
        • 67. 76
        • 68. 79
        • 69. 80
        • 70. 86
        • 71. 85
        • 72. 87
        Hints
        • Use SELECT * only if you need all columns from table
      • select `ecs_zp_goods`.*, `ecs_goods_zp`.`goods_id` as `pivot_goods_id`, `ecs_goods_zp`.`zp_id` as `pivot_zp_id`, `ecs_goods_zp`.`goods_number` as `pivot_goods_number`, `ecs_goods_zp`.`zp_number` as `pivot_zp_number`, `ecs_goods_zp`.`message` as `pivot_message`, `ecs_goods_zp`.`type` as `pivot_type`, `ecs_goods_zp`.`is_erp` as `pivot_is_erp`, `ecs_goods_zp`.`is_goods` as `pivot_is_goods`, `ecs_goods_zp`.`is_give` as `pivot_is_give` from `ecs_zp_goods` inner join `ecs_goods_zp` on `ecs_zp_goods`.`goods_id` = `ecs_goods_zp`.`zp_id` where `ecs_goods_zp`.`goods_id` = '929' and `ecs_goods_zp`.`start` <= '1746362814' and `ecs_goods_zp`.`end` > '1746362814' and `ecs_goods_zp`.`is_goods` = '0' and `ecs_goods_zp`.`zp_number` <= ecs_zp_goods.goods_number and `ecs_goods_zp`.`enabled` = '1' and `ecs_goods_zp`.`is_delete` = '0' and `ecs_zp_goods`.`goods_number` > '0' order by `ecs_goods_zp`.`goods_number` desc2.63msys_test
        Metadata
        Bindings
        • 0. 929
        • 1. 1746362814
        • 2. 1746362814
        • 3. 0
        • 4. 1
        • 5. 0
        • 6. 0
      • select `ecs_goods`.*, `ecs_goods_zp`.`goods_id` as `pivot_goods_id`, `ecs_goods_zp`.`zp_id` as `pivot_zp_id`, `ecs_goods_zp`.`goods_number` as `pivot_goods_number`, `ecs_goods_zp`.`zp_number` as `pivot_zp_number`, `ecs_goods_zp`.`message` as `pivot_message`, `ecs_goods_zp`.`type` as `pivot_type`, `ecs_goods_zp`.`is_erp` as `pivot_is_erp`, `ecs_goods_zp`.`is_goods` as `pivot_is_goods`, `ecs_goods_zp`.`is_give` as `pivot_is_give` from `ecs_goods` inner join `ecs_goods_zp` on `ecs_goods`.`goods_id` = `ecs_goods_zp`.`zp_id` where `ecs_goods_zp`.`goods_id` = '929' and `ecs_goods_zp`.`start` <= '1746362814' and `ecs_goods_zp`.`end` > '1746362814' and `ecs_goods_zp`.`is_goods` = '1' and `ecs_goods_zp`.`zp_number` <= ecs_goods.goods_number and `ecs_goods_zp`.`enabled` = '1' and `ecs_goods_zp`.`is_delete` = '0' and `ecs_goods`.`goods_number` > '0' order by `ecs_goods_zp`.`goods_number` desc7.77msys_test
        Metadata
        Bindings
        • 0. 929
        • 1. 1746362814
        • 2. 1746362814
        • 3. 1
        • 4. 1
        • 5. 0
        • 6. 0
      • select * from `ecs_miaosha_group_region` where `region_id` = '8'2.05msys_test
        Metadata
        Bindings
        • 0. 8
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_miaosha_group` where `start_time` <= '2025-05-04 20:46:54' and `end_time` > '2025-05-04 20:46:54' and `is_enabled` = '1' and isnull(delete_time) and `id` in ('2', '39', '1', '3', '4', '5', '7', '12', '15', '16', '17', '21', '24', '25', '33', '35', '40', '42', '43', '44', '45', '41', '48', '50', '54') limit 12.27msys_test
        Metadata
        Bindings
        • 0. 2025-05-04 20:46:54
        • 1. 2025-05-04 20:46:54
        • 2. 1
        • 3. 2
        • 4. 39
        • 5. 1
        • 6. 3
        • 7. 4
        • 8. 5
        • 9. 7
        • 10. 12
        • 11. 15
        • 12. 16
        • 13. 17
        • 14. 21
        • 15. 24
        • 16. 25
        • 17. 33
        • 18. 35
        • 19. 40
        • 20. 42
        • 21. 43
        • 22. 44
        • 23. 45
        • 24. 41
        • 25. 48
        • 26. 50
        • 27. 54
        Hints
        • Use SELECT * only if you need all columns from table
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • select `goods_id`, `user_price`, `kx_price`, `aba_price` from `ecs_member_price` where `ecs_member_price`.`goods_id` = '929' and `ecs_member_price`.`goods_id` is not null and `user_rank` = '1' limit 12.06msys_test
        Metadata
        Bindings
        • 0. 929
        • 1. 1
        Hints
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • select * from `ecs_goods_gallery` where `goods_id` = '929'2.44msys_test
        Metadata
        Bindings
        • 0. 929
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_miaosha_group_region` where `region_id` = '8'2.28msys_test
        Metadata
        Bindings
        • 0. 8
        Hints
        • Use SELECT * only if you need all columns from table
      • select * from `ecs_miaosha_group` where `start_time` <= '2025-05-04 20:46:54' and `end_time` > '2025-05-04 20:46:54' and `is_enabled` = '1' and isnull(delete_time) and `id` in ('2', '39', '1', '3', '4', '5', '7', '12', '15', '16', '17', '21', '24', '25', '33', '35', '40', '42', '43', '44', '45', '41', '48', '50', '54') limit 12.27msys_test
        Metadata
        Bindings
        • 0. 2025-05-04 20:46:54
        • 1. 2025-05-04 20:46:54
        • 2. 1
        • 3. 2
        • 4. 39
        • 5. 1
        • 6. 3
        • 7. 4
        • 8. 5
        • 9. 7
        • 10. 12
        • 11. 15
        • 12. 16
        • 13. 17
        • 14. 21
        • 15. 24
        • 16. 25
        • 17. 33
        • 18. 35
        • 19. 40
        • 20. 42
        • 21. 43
        • 22. 44
        • 23. 45
        • 24. 41
        • 25. 48
        • 26. 50
        • 27. 54
        Hints
        • Use SELECT * only if you need all columns from table
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • select * from `ecs_goods_statistics` where `goods_id` = '929' and `is_mtx` = '0' limit 12.13msys_test
        Metadata
        Bindings
        • 0. 929
        • 1. 0
        Hints
        • Use SELECT * only if you need all columns from table
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • update `ecs_goods_statistics` set `click_count` = '12', `update_time` = '2025-05-04 20:46:54' where `id` = '888'2.15msys_test
        Metadata
        Bindings
        • 0. 12
        • 1. 2025-05-04 20:46:54
        • 2. 888
      • select * from `ecs_ad` where `start_time` < '1746362814' and `end_time` > '1746362814' and `position_id` = '159' and `enabled` = '1' order by `sort_order` desc, `ad_id` desc2.16msys_test
        Metadata
        Bindings
        • 0. 1746362814
        • 1. 1746362814
        • 2. 159
        • 3. 1
        Hints
        • Use SELECT * only if you need all columns from table
      • select `name`, `url`, `opennew`, `id` from `ecs_nav` where `ifshow` = '1' and `type` = 'middle' and 1 = 1 order by `type` asc, `vieworder` asc2.15msys_test
        Metadata
        Bindings
        • 0. 1
        • 1. middle
      • select `name`, `url`, `opennew`, `id` from `ecs_nav` where `ifshow` = '1' and `type` = 'middle' and 1 = 1 order by `type` asc, `vieworder` asc2.13msys_test
        Metadata
        Bindings
        • 0. 1
        • 1. middle
      • select * from `ecs_jttj_goods` where `ecs_jttj_goods`.`goods_id` = '929' and `ecs_jttj_goods`.`goods_id` is not null and `is_enable` = '1' and `start_time` <= '1746362814' and `end_time` >= '1746362814' limit 12.06msys_test
        Metadata
        Bindings
        • 0. 929
        • 1. 1
        • 2. 1746362814
        • 3. 1746362814
        Hints
        • Use SELECT * only if you need all columns from table
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • select `cat_id`, `cat_name`, `sort_order` from `ecs_article_cat` where `cat_id` = '5' limit 11.97msys_test
        Metadata
        Bindings
        • 0. 5
        Hints
        • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      • select `cat_id`, `title`, `article_id`, `file_url`, `open_type`, `add_time`, `keywords` from `ecs_article` where `ecs_article`.`cat_id` in ('5') and `is_open` = '1' order by `article_type` desc, `article_id` desc limit 62.1msys_test
        Metadata
        Bindings
        • 0. 5
        • 1. 1
        _token
        3raZ3uLaN3f5cEi1SgHTWjEL9K1eyg2eKBNQsVJq
        PHPDEBUGBAR_STACK_DATA
        []
        format
        html
        content_type
        text/html; charset=UTF-8
        status_text
        OK
        status_code
        200
        request_query
        array:1 [ "id" => "929" ]
        request_request
        array:1 [ "id" => "929" ]
        request_headers
        array:10 [ "accept-encoding" => array:1 [ 0 => "gzip, deflate" ] "accept" => array:1 [ ...
        request_server
        array:36 [ "USER" => "apache" "HOME" => "/usr/share/httpd" "ORACLE_HOME" => "/usr/lib/oracle/2...
        request_cookies
        []
        response_headers
        array:3 [ "cache-control" => array:1 [ 0 => "no-cache" ] "date" => array:1 [ 0 => "Sun...
        path_info
        /goods
        session_attributes
        array:2 [ "_token" => "3raZ3uLaN3f5cEi1SgHTWjEL9K1eyg2eKBNQsVJq" "PHPDEBUGBAR_STACK_DATA" => [] ...